IRCT20181126041757N1尚未招募3 期
evaluation of the effectiveness of L-citrulline plus nCPAP versus solitary nCPAP in improvement of endothelium dysfunction and decreasing the severity of obstructive sleep apnea in patients undergoing polysomnography in Baharloo hospital and are categoriazed as moderate to serevere OSA
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 42
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- no limit 至 no limit（—）
- 性别
- All
入选标准
- •Patients who are categorized as moderate to severe according to AHI criteria by using polysomnography
- •The ones that clinical ultrasonography proves that the patient has endothelial dysfunction (FMD> NMD)
- •Patients the their arterial muscular dysfunction has been ruled out
排除标准
- •If less than 40 days have been passed from patien's OSA treatment
- •Hx of coronary artery disease (>50% of arterial occlusion, or any background PCI or CBAG)
- •Ischemic heart disease
- •Patients who do not have endothelial dysfunction (FMD ratio to normal vessel diameter is more than one)
- •Receiving any medication that affects endothelial function unless 4 half-life of the drug has been passed since its last consume.
研究者
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