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临床试验/NCT02854644
NCT02854644已完成不适用

Study of the Anti-tumoral Immune Response T Cells Cluster of Differentiation 4 (TCD4): Proof of the Concept in Breast Cancer and Glioma

Centre Hospitalier Universitaire de Besancon2 个研究点 分布在 1 个国家目标入组 167 人开始时间: 2014年1月27日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
167
试验地点
2
主要终点
Spontaneous immune responses of T cells CD4 specific tumor antigens

研究概览

简要总结

This study evaluates the frequency of the spontaneous T cells specific CD4 answers of tumoral antigens breast cancer and glioma.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Performance status 0,1 or 2
  • breast cancer or glioma
  • Arm glioma: patients without anti-tumoral treatment
  • Arm breast cancer: inclusion before treatment
  • Arm breast cancer HER2: patients with current therapy

排除标准

  • Psychiatric disease compromising the understanding of the information or the realization of the study
  • vulnerable People according to the law (minors, adults under protection, private persons of freedom ...)
  • Unaffiliated People to the Social Security
  • People being for the period of exclusion from another study
  • Life expectancy estimated unless 3 months.
  • For patients in Arm glioma: patients having already begun a systematic treatment.
  • For patients with a breast cancer: patient already under current therapy

结局指标

主要结局

Spontaneous immune responses of T cells CD4 specific tumor antigens

时间窗: 15 months

次要结局

  • T cells level(15 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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