the effect of antioxidant vitamins on blood coagulation during pregnancy in women at risk of preeclampsia

Phase 1

Completed

• Conditions: preeclampsia coagulopathy; Reproductive Health and Childbirth - Other reproductive health and childbirth disorders

• Registration Number: ACTRN12611000444987
• Lead Sponsor: magdy ameen elkady

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-05-02
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 251

Inclusion Criteria

Only pregnant women with high risk for pre-eclampsia were considered. The inclusion criteria were gestational age between 6-10 weeks with one or more of the following risk factors: pre-eclampsia in the pregnancy preceding the current one, eclampsia in any previous pregnancy, essential hypertension requiring medication, diagnosis of HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count), and chronic renal disease pre-pregnancy or during pregnancy

Exclusion Criteria

. Exclusion criteria included maternal liver disease, diabetes mellitus and possible materno-fetal fetus Rh incompatibility.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
preeclampsia : any case diagnosed as preeclampsia by hypertension, lower limb oedema,proteinuria[2nd and 3rd trimesters of pregnancy till the delivery]

Secondary Outcome Measures

Name	Time	Method
coagulopathy indicated by d-dimer[every trimester( 3 month )]