Early Detection of Lung Cancer In Patients With Chronic Chest Diseases

Not yet recruiting

• Conditions: Chest--Diseases

• Registration Number: NCT06074978
• Lead Sponsor: Assiut University

Brief Summary

* To evaluate the effectiveness of LDCT in detecting early-stage lung cancer in patients with chronic lung conditions compared to standard chest x-rays.

* To improve lung cancer outcomes through optimized use of radiological technologies for early detection in high-risk patients with pre-existing lung conditions.

Detailed Description

The early detection of lung cancer is crucial, as it is one of the most common and deadly types of cancer worldwide. Early detection is especially important in patients with chronic chest diseases, as these underlying conditions can make lung cancer more difficult to diagnose at later stages. Radiological imaging techniques play a key role in the early detection of lung cancer in this high-risk patient population.

Recent advances in imaging technologies have improved our ability to detect small lung abnormalities indicative of cancer at earlier stages, even before symptoms appear . Techniques such as low-dose CT scanning have been shown to reduce lung cancer mortality by up to 20% compared to chest radiography alone . Advanced imaging allows clinicians to identify subtle nodules or masses in the lungs that may represent cancer .

Determining the type, size, and extent of lung lesions is important for prognosis and treatment planning . Imaging technologies help characterize lesions as benign or malignant and determine cancer stage . This information guides decisions around surgery, chemotherapy, radiation therapy, or other interventions .

Early detection through radiological screening has been associated with improved survival rates for lung cancer patients with chronic lung diseases . Screening finds a higher portion of early-stage, potentially curable cancers in this high-risk group . Overall, advanced imaging techniques play a vital role in the early detection and management of lung cancer in patients with underlying chronic chest conditions.

Study Timeline

• Status Verified: 2023-10
• Study First Submitted: 2023-10-01
• Study First Submitted QC: 2023-10-06
• Study First Posted: 2023-10-10
• Last Update Submitted: 2023-11-03
• Last Update Posted: 2023-11-07
• Study Start: 2023-12-20
• Primary Completion: 2024-10-20
• Study Completion: 2024-12-20

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1- Chronic chest diseases Patients .

Exclusion Criteria

1 - Age: less than 45 years. 2-Patients diagnosed with lung cancer 3-Unstable patients or need for ICU admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection early-stage lung cancer (Stage I/II) • Lung • Lung cancer mortality rate	baseline	By LDCT

Secondary Outcome Measures

Name	Time	Method
• Diagnostic accuracy of imaging modalities • Positive predictive value of screening tests • Rate of unnecessary invasive procedures • Identification of high-risk subgroups	baseline	BY statiscal anylasis from results