Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis

Withdrawn

• Conditions: Sepsis

• Registration Number: NCT01903668
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

Step 1: Identification and characterisation of the TREM1L protein from samples already available characterised at the hospital Central of Nancy Step 2: Study of the isoforms of TREM1L in correlation with the prognosis of sepsis, Step 3: implementation of assay methods for TREM1L (ELISA or SUPRA MS) Step 4: Validation of assays for TREM1L and its isoforms in a larger number of subjects (inclusion of samples from Dijon CHU and Besançon CHU)

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04
• Status Verified: 2013-07
• Study First Submitted: 2013-07-17
• Study First Submitted QC: 2013-07-17
• Last Update Submitted: 2013-07-17
• Study First Posted: 2013-07-19
• Last Update Posted: 2013-07-19
• Primary Completion: 2014-04

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• patients hospitalised in a Medical Intensive Care unit whatever the reason
• written informed consent obtained

Exclusion Criteria

• patients less than 18 years old or under guardianship, persons without national health insurance.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
plasma concentrations of sTREM-1	baseline