Diclofenac Potassium Alone Versus Diclofenac Potassium With Hyoscine-N-butyl Bromide (HBB in Endoscopy

Not Applicable

Completed

• Conditions: Pain
• Interventions: Diagnostic Test: Diclofenac + HBB with hysteroscopy; Diagnostic Test: Diclofenav + placebo

• Registration Number: NCT04125771
• Lead Sponsor: Aljazeera Hospital

Brief Summary

Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions.

Detailed Description

Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and chronic pain and inflammatory conditions.

. As with all NSAIDs, diclofenac exerts its action via inhibition of prostaglandin synthesis by inhibiting cyclooxygenase-1 (COX-1)

Study Timeline

• Study First Submitted: 2019-10-11
• Study First Submitted QC: 2019-10-11
• Study First Posted: 2019-10-14
• Study Start: 2020-02-16
• Primary Completion: 2020-08-25
• Study Completion: 2020-10-01
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-31
• Last Update Posted: 2021-11-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• 1. Patients indicated for diagnostic hysteroscopy including infertility, bleeding, suspected intrauterine pathologies (eg polypi , septea) 2. Reproductive age 20 - 40yrs

Exclusion Criteria

• 1. Menopausal and amenorrhic patients 2. Contraindication to office hysteroscopy such as:- pelvic inflammatory disease, marked cervical stenosis, pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Diclofenav + placebo	Diclofenac + HBB with hysteroscopy	Women who will receive Diclofenav + placebo
Diclofenac + HBB	Diclofenac + HBB with hysteroscopy	Women who will receive Diclofenac + HBB
Diclofenac + HBB	Diclofenav + placebo	Women who will receive Diclofenac + HBB
Diclofenav + placebo	Diclofenav + placebo	Women who will receive Diclofenav + placebo

Primary Outcome Measures

Name	Time	Method
The number of women who will not feel pain	within half an hour	the effect of medications on pain sensation

Trial Locations

Locations (1)

Algazeerah and Kasralainy hospital; 🇪🇬 Giza, Egypt