A randomized controlled trial on acupuncture treatment of diarrheal-predominant irritable bowel syndrome
- Conditions
- Irritable bowel syndrome
- Registration Number
- ITMCTR2100004642
- Lead Sponsor
- Beijing University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Aged between 18 and 75 years (no gender limitation);
2. Meets the diagnostic criteria of diarrheal-predominant irritable bowel syndrome (IBS-D);
3. Type 6 or 7 of the Bristol Stool Form Scale appeared for at least 4 days and type 1 or 2 appeared for less than 4 days in last 2 weeks; The average score of daily abdominal pain was >= 3 in the last week;
4. No treatment of acupuncture in the last 6 months;
5. No use of antidepressant or IBS medication within 2 weeks before treatment, including traditional Chinese medicine (TCM) or proprietary Chinese medicine, antidiarrheal, antispasmodic, intestinal antibiotics, probiotics and so on.
1.Patients with the following diseases: inflammatory bowel disease, microscopic colitis, celiac disease, Crohn's disease and other organic bowel diseases;
2.Diabetes mellitus and abnormal thyroid function;
3.Severe acute or chronic organic diseases, kidney or liver diseases;
4.History of abdominal surgery (appendectomy, hemorrhoidectomy, or polypectomy greater than 3 months post-surgery are allowed.);
5.Pregnancy or lactation;
6.History of alcohol and drug abuse;
7.Participating in other clinical trials.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Effective response rate;
- Secondary Outcome Measures
Name Time Method IBS symptom severity scale, IBS-SSS;defecation frequency;Symptoms of bloating;Effective response rate at other time points;Symptoms of abdominal pain;Quality of life questionnaire, IBS-QOL;IBS-AR;Patient Health Questionnaire Depression Scale;