Psychobiological predictors of the outcome after stem cell transplantatio
- Conditions
- Patients with an indication for allogenic stem cell transplantation: - acute myeloid leukemia (AML)- acute lymphoblastic leukemia (ALL)- myeloproliferative neoplasm (MPS)- myelodysplastic syndrome (MDS)
- Registration Number
- DRKS00023754
- Lead Sponsor
- Fachbereich MedizinKlinik für Hämatologie, Onkologie und Immunologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 55
Inclusion Criteria
indication for allogenic stem cell transplantation; age > 18 years; sufficient German language skills; (cognitive) ability to give informed consent
Exclusion Criteria
no indication for scheduled stem cell transplantation
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients' illness-related disability (Pain Disability Index (PDI)) 6 months after stem cell transplantation
- Secondary Outcome Measures
Name Time Method - subjective quality of life<br>- negative effects of the medical treatment/side effects<br>- treatment-related expectations<br>- optimism<br>- illness-beliefs<br>- anxiety and depressive symptoms<br>- physical activity<br>- beliefs about medication<br>- inflammatory and immunological parameters (T-cells, CRP, IL-6, IL-8, molecular diagnostics)<br>- acute graft-vs.-host-disease (GvHD)<br>- chronic GvHD<br>- relapse within first year<br>- length of hospital stay<br>- complications <br>- infections<br>- days until leukocyte engraftment (leucocytes >1 g/l)<br>- mortality<br>- transplantation-associated mortality 100 days after transplantation<br>- molecular analyses