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临床试验/CTRI/2024/10/074826
CTRI/2024/10/074826招募中不适用

Preoperative ultrasound guided estimation of subclavian vein diameter changes by passive leg rising to assess the incidence of post-induction hypotension after General anaesthesia in patients of head and neck malignancies: A Prospective Observational Study

All India Institute of Medical Sciences New Delhi1 个研究点 分布在 1 个国家目标入组 152 人开始时间: 2024年10月20日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
152
试验地点
1
主要终点
To assess whether the ultrasonographic measurement of Subclavian vein diameter changes by passive leg rising will be able to predict hypotension after induction of general anaesthesia in patients of head and neck malignancies.

研究概览

简要总结

Postinduction hypotension can occur during the early phase of anesthesia, typically within 20 minutes after the induction of general anesthesia. Several factors contribute to postinduction hypotension. General anesthetic agents can cause vasodilation, leading to decreased systemic vascular resistance and subsequent hypotension.Reduced blood volume due to inadequate fluid status or preoperative fasting can contribute to the same patient characteristics like age, comorbidities, and medications the patient is taking all may have an effect.Prolonged hypotension during surgery can have significant consequences for patients. Prolonged low blood pressure can impair perfusion to vital organs and may lead to myocardial injury, acute kidney injury, cerebral ischemia etc. So it is of paramount importance to identify the risk groups prior to induction and manage the hypotension judiciously. Pre-induction ultrasonography of IJV was used to predict post-induction hypotension and SCV collapsibility index in deep inspiration has been shown to predict hypotension after induction of GA.

We hypothesize that the subclavian vein diameter changes induced by passive leg rising can be used to estimate intravascular fluid status and can be an indicator of incidence of hypotension after general anaesthesia. Therefore we aim to evaluate the the predictive power of ultrasound guided diameter changes of subclavian vein in the spontaneous breathing PLR position.for post induction hypotension

研究设计

研究类型
Interventional

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1,Patients with age between18 to 70 years and American Society of Anaesthesiologists (ASA) Physical Status class I, II and III: 2,Patients undergoing elective head and neck oncological malignancies.

排除标准

  • patient refusal patients belonging to ASA 4 and 5 severe renal, hepatic, cardiac failure signs of fluid overload before anaesthesia.

结局指标

主要结局

To assess whether the ultrasonographic measurement of Subclavian vein diameter changes by passive leg rising will be able to predict hypotension after induction of general anaesthesia in patients of head and neck malignancies.

时间窗: up to 10 minutes after induction of anaesthesia

次要结局

  • To assess the predictive ability of subclavian vein collapsibility index for the incidence of post-induction hypotension in patients of head and neck malignancies(upto 10 minutes after induction of anaesthesia)
  • To assess the predictive maximum diameter of subclavian vein in passive leg rising position for the incidence of post-induction hypotension in patients of head and neck malignancies(upto 10 minutes after induction of anaesthesia)

研究者

发起方
All India Institute of Medical Sciences New Delhi
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Roopesh R

All India Institute of Medical Sciences, New Delhi

研究点 (1)

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