Major Adverse Cardiac Events occurring during non cardiac surgery in cardiac patients: How accurately cardiac biomarkers predict the occurrence of these Events?

Not Applicable

• Conditions: Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

• Registration Number: CTRI/2019/06/019599
• Lead Sponsor: Postgraduate Institute of Medical Education and Research Chandigarh

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Closed to Recruitment of Participants
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients with prior history of coronary artery disease will be defined as having any one of the following:

i)Definite CAD as indicated by a previous history of MI, typical angina or ECG changes suggestive of previous MI without a documented history of MI

ii)Patient who underwent coronary artery reperfusion therapy including previous fibrinolytic therapy, percutaneous coronary intervention and coronary angioplasty.

Patient at risk of coronary artery disease will be defined as those with age 45 yr or older and had at least one of the following major cardiac risk factors34:

1) Diabetes mellitus

2) Peripheral artery disease (i.e. intermittent claudication or history of vascular surgery except arteriovenous shunt and vein-stripping procedures)

3) History of hospitalization for congestive heart failure

4) Renal insufficiency (defined as preoperative creatinine >150 µmol litre-1)

5) History of cerebral vascular event

6) Aortic valve stenosis (defined as aortic valve area <1 cm2)

7) Atrial fibrillation

8) Moderate or poor left ventricular function (defined as left ventricular ejection fraction <55%)

Exclusion Criteria

Patients will be excluded from study participation if they had no signed informed consent.

Study & Design

• Study Type: Observational
• Study Design: Not specified