OPEN LABEL STUDY TO EVALUATE THE EFFICACY, SAFETY AND TOLERABILITY OF HYZAARTM (LOSARTAN 50 MG / HCTZ 12.5 MG) IN PATIENTS WITH ESSENTIAL HYPERTENSION INADEQUATELY CONTROLLED WITH VALSARTAN MONOTHERAPY OF 80 MG AND TO WHICH THE THERAPY WAS CHANGED

Not Applicable

Completed

• Conditions: -I10 Essential (primary) hypertension; Essential (primary) hypertension; I10

• Registration Number: PER-017-05
• Lead Sponsor: MERCK & CO.INC.,

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-05-18
• Last Update Posted: 4 September 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

a. Between 18 and 75 years of age.
b. Sex: Both male and female patients are acceptable.
c. Hospitalization status: Outpatient.
d. The patient suffers from essential hypertension.
e. Patients must have grandparents by their mother or father / biological parents of patients born in Asia.
f. Blood pressure
• At visit 1 with a SiDBP> 85 to <95 mmHg.
• In visit 2 that show a SiDBP between 95 and 115 mmHg
• At Visit 3 only patients who are not controlled will be switched to HYZAAR ™.
g. The patient is legally capable and can understand the nature and implications of the clinical study.
h. The patient wants to participate in this study.

Exclusion Criteria

a) The patient is pregnant or is breastfeeding.
b) The patient has known or suspected secondary hypertension.
c) The patient has a history of malignant hypertension.
d) The patient has a systolic blood pressure while sitting (SiSBP)> 190 mmHg.
e) The patient has a history of stroke
f) Patients with a history of myocardial infarction within the last 6 months.
g) Patient with active history of angina that has not stabilized with medical therapy.
h) Patients who have undergone percutaneous coronary intervention or aortocoronary bypass surgery within the previous 6 months.
i) Patients with atrioventricular block (second or third degree).
j) Patients with complete blockage of the left fascicular branch.
k) Patients with atrial fibrillation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified