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Clinical Trials/NCT05076929
NCT05076929
Completed
Not Applicable

Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia

Ain Shams University1 site in 1 country60 target enrollmentMay 28, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Hypovolemia, Cerebrospinal
Sponsor
Ain Shams University
Enrollment
60
Locations
1
Primary Endpoint
mean arterial blood pressure
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Administration of intravascular fluids is one of the methods to prevent SA-induced hypotension, but empirical intraoperative volume repletion carries the risk of fluid overload during elective surgery. Over fluid resuscitation is associated with organ dysfunction and higher mortality rate , thus, to avoid ineffective or even harmful intravascular volume expansion, it is important to have tools to predict hypotension and fluid responsiveness.

Registry
clinicaltrials.gov
Start Date
May 28, 2021
End Date
March 1, 2022
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mona Ammar

Assistant Professor

Ain Shams University

Eligibility Criteria

Inclusion Criteria

  • ASA grade I, II, III
  • Age 18 -65 yrs
  • Spinal Anesthesia

Exclusion Criteria

  • Patient refusal
  • Patient having contraindication of Spinal Anesthesia (infection at the site of injection, spine deformity, coagulation disorders ) .
  • Known cardiac, renal, neurological, metabolic, endocrine, psychiatric, respiratory disease.

Outcomes

Primary Outcomes

mean arterial blood pressure

Time Frame: 15 minutes after tourniquet release

Study Sites (1)

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