Assessment of Ultrasonographic Measurement of Inferior Vena Cava Collapsibility Index in Prediction of Hypotension Associated With Tourniquet Release in Total Knee Replacement Surgeries Under Spinal Anesthesia

Completed

• Conditions: Fluid Hypovolemia, Cerebrospinal

• Registration Number: NCT05076929
• Lead Sponsor: Ain Shams University

Brief Summary

Administration of intravascular fluids is one of the methods to prevent SA-induced hypotension, but empirical intraoperative volume repletion carries the risk of fluid overload during elective surgery. Over fluid resuscitation is associated with organ dysfunction and higher mortality rate , thus, to avoid ineffective or even harmful intravascular volume expansion, it is important to have tools to predict hypotension and fluid responsiveness.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-05-28
• Study First Submitted: 2021-09-26
• Study First Submitted QC: 2021-10-12
• Study First Posted: 2021-10-13
• Primary Completion: 2022-02-01
• Study Completion: 2022-03-01
• Status Verified: 2022-09
• Last Update Submitted: 2022-09-29
• Last Update Posted: 2022-10-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA grade I, II, III
• Age 18 -65 yrs
• Spinal Anesthesia

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Exclusion Criteria

• Patient refusal
• Patient having contraindication of Spinal Anesthesia (infection at the site of injection, spine deformity, coagulation disorders ) .
• Known cardiac, renal, neurological, metabolic, endocrine, psychiatric, respiratory disease.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
mean arterial blood pressure	15 minutes after tourniquet release

Trial Locations

Locations (1)

Ain Shams University; 🇪🇬 Cairo, Egypt