跳至主要内容
临床试验/NCT07658625
NCT07658625已完成不适用

Association Between Oral Hypofunction, Sarcopenia, and Social Frailty in Community-Dwelling Older Adults

Chang Gung University of Science and Technology1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2025年11月14日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1
主要终点
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.

研究概览

简要总结

Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community.

This study,the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Group A-Inclusion Criteria:
  • 65 years old or above
  • general public or institutionalized for 3 months or more
  • those who accept the experimental design and are willing to sign the consent form
  • dietary sources are oral intake
  • those who are diagnosed as having possible sarcopenia by researchers
  • Group B-Inclusion Criteria:
  • 65 years old or above
  • general public or institutionalized for 3 months or more
  • those who accept the experimental design and are willing to sign the consent form
  • dietary sources are oral intake
  • those who were determined by researchers to be non-probable sarcopenia

排除标准

  • comorbidities, critical illness, pre- and post-major surgery, cancer, renal failure, liver failure, kidney disease, liver disease, malignant tumors within the past five years, inflammatory conditions (c-reactive protein >10mg/dL)
  • severely malnourished people
  • long-term force-feeding

研究组 & 干预措施

Group B

Non-possible sarcopenia

干预措施: Non interventional study (Other)

Group A

Possible sarcopenia

干预措施: Non interventional study (Other)

结局指标

主要结局

Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.

时间窗: Baseline

* The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Association Between Oral Hypofunction, Sarcopenia... | 临床试验