Telecom System to Improve Adherence to Antidepressants

Boston Medical Center1 site in 1 country144 target enrollmentApril 2003

ConditionsDepression

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Depression
Sponsor: Boston Medical Center
Enrollment: 144
Locations: 1
Primary Endpoint: Antidepressant medication adherence
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study will determine the efficacy of a computerized telephone system called Telephone-Linked Care (TLC) in improving adherence to antidepressant medication regimens in people with depression.

Detailed Description

The purpose of this study is to test the efficacy of a computerized telephone system called TLC (Telephone-Linked Care) in helping subjects adhere to their antidepressant medication regimens.

Registry

clinicaltrials.gov

Start Date

April 2003

End Date

January 2006

Last Updated

12 years ago

Study Type

Interventional

Study Design

Factorial

Sex

All

Investigators

Sponsor

Boston Medical Center

Eligibility Criteria

Inclusion Criteria

•A clinical diagnosis of major depressive disorder, dysthymic disorder, depressive disorder not otherwise specified, or any combination of the three
•Prescribed at least one antidepressant medication
•Access to a telephone with touch-tone service
•Speak and understand conversational English

Exclusion Criteria

•Current significant alcohol or drug abuse
•Clinical diagnosis of bipolar disorder, schizoaffective disorder, or significant personality disorder
•Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis (ALS), or other neurodegenerative diseases
•Alzheimer's disease and other dementia
•Cancer, undergoing radiation therapy or chemotherapy
•Suffering from Renal disease or on dialysis
•Immunologic disorder (rheumatoid arthritis, systemic lupus erythematosus \[SLE\], etc.)
•Terminal illness
•Legally blind
•Planning to leave the geographic area during the study period

Outcomes

Primary Outcomes

Antidepressant medication adherence

Time Frame: Measured monthly for 4 months

Adherence to scheduled psychiatry clinic visits

Time Frame: Measured monthly for 4 months

Secondary Outcomes

Depression status, measured by self-administered depression inventory scale(Measured at baseline and at 4 month follow-up)
General health status, measured by self-rating health survey(Measured at baseline and at 4 month follow-up)