Obsessive-compulsive Symptoms in Children and Adolescents With Anorexia Nervosa and Possible Correlation With BMI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Prevalence of obsessive compulsive symptoms
研究概览
简要总结
The purpose of this study is to determine obsessive-compulsive symptoms and BMI changes in children and adolescents with anorexia nervosa and find out whether there is a group-level correlation between the two. We also investigate a possible link between obsessive compulsive symptoms and the psychological features of eating disorders.
It is a national, academic, interventional study. The data will be acquired through questionnaires.
详细描述
Children and adolescents with anorexia nervosa show a high psychiatric co-morbidity. In clinical practice, compulsions and compulsive thoughts are frequently reported in children and adolescents with anorexia nervosa. Obsessive compulsive disorder occurs in 19% of patients with anorexia nervosa and anorexia nervosa is seen in 3-17% of female patients with obsessive compulsive disorder.
A precise explanation for this coexistence is still unknown.An underlying genetic correlation and common neuropsychological factors and personality traits are described in the literature as possible explanations. Little is know about the relation between obsessive compulsive symptoms and the psychological features of eating disorders.
It is also unclear whether obsessive compulsive symptoms can be seen as a result of the underweight and weight loss associated with anorexia nervosa and whether these symptoms clear up with weight recovery. Research on this is very limited and shows different results. The aim of this study is to examine obsessive compulsive symptoms and weight change in children and adolescents with anorexia nervosa and to determine whether there is a group-level correlation between the two.
It is a national, academic, interventional study. The data will be acquired through the following questionnaires:
- Questionnaires to be completed by the minor:
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 10 Years 至 18 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Dutch-speaking female patients with parents who have sufficient command of Dutch
- •Minors from 10 years up to and including 18 years old
- •Known with the diagnosis of anorexia nervosa and registered for treatment in Paika Food Clinic Service (outpatients and/or inpatients)
- •Informed consent obtained from the minor herself and parent (s) / guardian
排除标准
- •Patients or parents of patients who do not have sufficient command of Dutch
- •Male patients
- •Minors <10 years and adults older than 18 years
- •Minors and / or parent (s) / guardians have not given written permission to participate
研究组 & 干预措施
research group
patients who are willing to participate in the study
干预措施: Questionnaires (Other)
结局指标
主要结局
Prevalence of obsessive compulsive symptoms
时间窗: through study completion, an average of 1 year
current obsessive compulsive symptoms are identified using the CY-BOCS Symptom Checklist (17 different categories of obsessive compulsive behaviour en thoughts, each scored by 0 (if absent) or 1 (if present). A total score is calculated by taking the mean of all 17 categories (=' total number of obsessive compulsive symptoms').
Severity of obsessive compulsive symptoms
时间窗: through study completion, an average of 1 year
severity of symptoms are identified using the CY-BOCS Severity Ratings score between minimum value 0 (no impact on daily life) and maximum value 40 (high impact on daily life)
次要结局
- Correlation between the severity and total number of obsessive compulsive symptoms and BMI(through study completion, an average of 1 year)
- Correlation between obsessive compulsive symptoms (severity and total number) and EDI-3 subscales(through study completion, an average of 1 year)
研究者
Lisa Cornelis
Principal Investigator
Universitair Ziekenhuis Brussel