To study the effectiveness of umbilical cord blood transfusion in neonates at tertiary health care centre
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- mortality of subjects
研究概览
简要总结
Objective: To determine the usefulnessof umbilical cord blood (UCB) as an alternative to adult blood (AB) in neonatesand to compare change in haematological parameters after transfusion &compare outcomes. Study design: It was an interventional study of UCB transfusionsgiven to neonates requiring blood. UCB was collected in labour Room, under allaseptic precautions, and pretesting were done in blood bank. Neonates fulfilling inclusion criteria were included. UCBand AB was given as per availability and consent. Post blood analysis was doneafter 6 hours of transfusion, watched for reactions. Outcomes like death,discharge and duration of hospital stay were analysed. Results: A total of 91 blood transfusion were performed, out of which 34 receivedUCB and 57 with AB. Mean rise of haemoglobin in UCB transfused patient was2.01gm/dl. Conclusion: In neonates requiring bloodtransfusion whole UCB is a good and safe alternative of whole AB.
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 1.00 Day(s) 至 28.00 Day(s)（—）
- 性别
- All
入选标准
- •Neonates >34 week gestation admitted in NICU requiring Blood Transfusion & whose parents gave legal consent for the procedure.
排除标准
- •1.Patient who were not willing for the procedure.
- •Neonates who have earlier h/o blood transfusion.
- •Syndromic Neonates and those with Congenital Anomaly.
- •Neonates with hemolytic disease.
结局指标
主要结局
mortality of subjects
时间窗: Appearance of side effects : at the time of tranfusion | 1 hour after transfusion | 2 hour after transfusion | Mortality of subjects: at the time of discharge
appearance of side effects
时间窗: Appearance of side effects : at the time of tranfusion | 1 hour after transfusion | 2 hour after transfusion | Mortality of subjects: at the time of discharge
次要结局
- usefulness of umblical cord blood transfusion in neonatal care(from admission in nicu to discharge.)