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Clinical Trials/NCT07455786
NCT07455786RecruitingNot Applicable

Modified Trabeculectomy for Management of Early Failure of Combined Phaco With GATT or With Goinopuncture

Assiut University1 site in 1 country20 target enrollmentStarted: April 1, 2026Last updated:
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
20
Locations
1
Primary Endpoint
IOP

Study Overview

Brief Summary

These procedures include deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule.

Detailed Description

Since the advent of GATT or phacogoinotomy as MIGS, ab-externo canaloplasty and NPDS have become essentially obsolete. The ab-interno techniques to vasodilate Schlemm's canal and goniotomy have largely replaced ab-externo canaloplasty.

. Although the GATT procedure and phacogoinotomy is, minimally invasive methods, yet it needs normal functional collector orifice and not respect physiological function of trabecular meshwork,8 as these procedures depend mainly on incision and damage of trabecular meshwork360 degree in GATT 120 in goniotomy, the main disadvantage of these procedures it is not so suitable for narrow angle glaucoma and have many complications as post operative hyphemia with IOP spike, PAS, corneal injury and create cyclodialysis Moreover trabecular meshwork and Schlemm's canal are vital structures can repair themselves through limbal stem cells or even peripheral iris can cover the incision as the part of repair. The main disadvantage is that the trabeculectomy should not be relied upon when the target IOP is in the low teens. Also, these procedures are expensive and need a long learning curve, hyphemia can prevent completion of the operation.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
21 Years to 70 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • All patients had combined phaco surgery with GATT.
  • All patients had phaco with goinopuncture.

Exclusion Criteria

  • Healthy patient.
  • No history of phaco surgery with GATT or goinopuncture.

Arms & Interventions

Modified Trabeculectomy

Experimental

failure of combined phaco with GATT

Intervention: Modified trabeculectomy (Procedure)

Outcomes

Primary Outcomes

IOP

Time Frame: 24 hours

Intraocular pressure measurement

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Hassan Lotfy Fahmy

Prof

Assiut University

Study Sites (1)

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