Usefulness of Procalcitonin Test to Differentiate the Cause of Pneumonia in Patients With Cancers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 649
- 试验地点
- 1
- 主要终点
- Procalcitonin level according to the cause of pneumonia in patients with cancer
研究概览
简要总结
The purpose of this study is to evaluate the usefulness of procalcitonin test for differentiation of the cause of pneumonia in patients with cancer.
详细描述
Serum procalcitonin test is currently used as the biomarker for bacterial infection. Especially, procalcitonin test has been reported to be helpful in differentiating bacterial pneumonia from viral pneumonia, acute exacerbations of interstitial pneumonitis or chronic obstructive lung disease. However, it is not known whether procalcitonin test can help distinguish bacterial pneumonia from non-bacterial pneumonia such as radiation pneumonitis or chemotherapy-induced pneumonitis in patients with cancer.
The aim of this prospective cohort study is to observe the clinical benefits of procalcitonin test for differentiation of the cause of pneumonia in patients with cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age greater than 18 years
- •Patients who have symptoms and suspected imaging findings compatible with pneumonia
排除标准
- •Patients who have been treated with antibiotics or steroid therapy.
结局指标
主要结局
Procalcitonin level according to the cause of pneumonia in patients with cancer
时间窗: procalcitonin level is checked within 24hours after visiting hospital
bacterial pneumonia vs. radiation pneumonitis vs chemotherapy-induced pneumonitis
次要结局
- Influence of neutropenia on procalcitonin level in patients with baterial pneumonia(procalcitonin level is checked within 24hours after visiting hospital)
- procalcitonin level in patients with atypical pneumonia(procalcitonin level is checked within 24hours after visiting hospital)
研究者
Hee Seok Lee
Pulmonologist
National Cancer Center, Korea