ISRCTN43803769已完成未知
ASCRIBED: The impact of Acute SystematiC inflammation upon cerebRospinal fluId and blood BiomarkErs of brain inflammation and injury in Dementia: a study in acute hip fracture patients
niversity of East Anglia0 个研究点目标入组 469 人开始时间: 2017年5月11日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 469
研究概览
简要总结
2019 Protocol article in https://pubmed.ncbi.nlm.nih.gov/31493787/ protocol (added 09/12/2020)
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •Group 1: Pre-operative acute hip fracture patients with confusion as defined by the Abbreviated Mental Test (England) or 4AT (Scotland):
- •Inclusion Criteria:
- •1. Patient must have had a confirmed proximal hip fracture requiring an operation and be aged 60 or older at the time of operation
- •2. Patient has a pre-operative Abbreviated Mental Test score of 8 or below or 4AT score of 1 or above
- •3. Patient must be undergoing spinal anaesthesia
- •Group 2: Pre-operative acute hip fracture patients without confusion as defined by the Abbreviated Mental Test (England) or 4AT (Scotland):
- •Inclusion Criteria:
- •1. Patient must have had a confirmed proximal hip fracture requiring an operation and be aged 60 or older at the time of operation
- •2. Pre-operative Abbreviated Mental Test score of 9 or above or 4AT score of 0
- •3. Patient must be undergoing spinal anaesthesia
排除标准
- •Group 1 and 2:
- •1. Decision taken not to have hip surgery
- •2. Patient has head trauma with bleeding as indicated by a CT scan
- •3. Patient has confirmed diagnosis of Parkinson’s disease
- •4. Patient not expected to survive beyond 4 weeks
研究者
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