Effects of Nicotine in Tobacco Smokers

Phase 1

Completed

• Conditions: Smoking, Tobacco; Smoking (Tobacco) Addiction
• Interventions: Drug: Cigarette 1; Drug: Cigarette 2; Drug: Patch 1; Drug: Patch 2

• Registration Number: NCT03651869
• Lead Sponsor: University of Southern California

Brief Summary

This study will examine mechanisms linking Obsessive-Compulsive Disorder symptomatology to tobacco dependence.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-08-23
• Study First Submitted QC: 2018-08-27
• Study First Posted: 2018-08-29
• Study Start: 2019-02-04
• Primary Completion: 2023-03-23
• Study Completion: 2023-03-23
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-11
• Last Update Posted: 2023-07-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 221

Inclusion Criteria

• At least 21 years old
• Daily smoking at least 2 years

Exclusion Criteria

• Currently pregnant or breastfeeding.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Condition 1	Cigarette 1	-
Condition 1	Patch 1	-
Condition 2	Cigarette 2	-
Condition 2	Patch 1	-
Condition 3	Cigarette 1	-
Condition 3	Patch 2	-
Condition 4	Cigarette 2	-
Condition 4	Patch 2	-

Primary Outcome Measures

Name	Time	Method
Smoking Urge	Throughout study completion, an average of two weeks.	Smoking urge is measured using questionnaires that ask about a desire to smoke.

Trial Locations

Locations (1)

University of Southern California; 🇺🇸 Los Angeles, California, United States