Investigating the effect of chest physiotherapy in children with cystic fibrosis
Not Applicable
Recruiting
- Conditions
- Cystic fibrosis with pulmonary manifestations.E84.0Cystic fibrosis with pulmonary manifestations
- Registration Number
- IRCT20240622062217N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Consent to participate in the study
Having cystic fibrosis
Suspected respiratory infection as diagnosed by the attending physician
Having no underlying disease other than cystic fibrosis
Exclusion Criteria
Cystic fibrosis patients who do not have pulmonary involvement
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Positive culture results in two samples before and after chest physiotherapy. Timepoint: Pharynx culture sample before and after chest physiotherapy. Method of measurement: Retropharyngeal sample with sterile cotton swab.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link chest physiotherapy to mucus clearance in cystic fibrosis (E84.0) patients?
How does chest physiotherapy compare to hypertonic saline or dornase alfa in improving pulmonary function in pediatric cystic fibrosis?
Which biomarkers (e.g., sputum IL-8, CFTR function) predict response to chest physiotherapy in IRCT20240622062217N1?
What adverse events (e.g., rib fractures, mucus plugging) are associated with chest physiotherapy in pediatric cystic fibrosis trials?
How do combination approaches (e.g., physiotherapy + mucolytics) enhance airway clearance in CFTR-mutant cystic fibrosis patients?