Skip to main content
Clinical Trials/NCT00336180
NCT00336180
Completed
Phase 2

Adolescent Drug and HIV Prevention in South Africa

Penn State University1 site in 1 country7,695 target enrollmentSeptember 2003

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Substance-Related Disorders
Sponsor
Penn State University
Enrollment
7695
Locations
1
Primary Endpoint
incidence of ATOD use
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

The purpose of this trial is to test the effectiveness of a classroom-based prevention program (HealthWise: Learning Life Skills for Young Adults) to reduce the risk of HIV/AIDS and STIs, as well as substance use, among adolescents in one area of South Africa.

Detailed Description

Recent estimates of the incidence of HIV among South African youth reveal rates to be among the highest in the world. Research shows that the sexual behaviors that put youth at increased risk for HIV often occur in the context of substance use. Consequently, effective prevention programs will most likely target both types of risk behavior. Research and theory also suggest that a positive youth development approach may be an useful way to reduce risk behavior. Therefore, our study involves the implementation of a classroom-based leisure, life-skill, and sexuality education curriculum, HealthWise: Learning Life Skills for Young Adults. This program is designed to reduce substance use and sexual risk behavior and to increase healthy leisure behavior and intra- and interpersonal skills. Students from 4 high schools are currently receiving the HealthWise lessons in the 8th and 9th grades; students from 5 other schools serve as controls. Participants complete survey assessments on PalmPilots twice per year, until they leave school. Three cohorts of students are participating in this trial. Our hypothesis is that HealthWise participants will engage in less risk behavior than controls. This will be tested using various statistical methodologies, including multiple regression, structural equation modeling, and growth modeling.

Registry
clinicaltrials.gov
Start Date
September 2003
End Date
April 2008
Last Updated
13 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Edward A. Smith

Interim Director

Penn State University

Eligibility Criteria

Inclusion Criteria

  • attending one of nine secondary schools involved in the HealthWise South Africa research trial

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

incidence of ATOD use

Time Frame: 2 years

incidence of lifetime sexual intercourse

Time Frame: 2 years

rates of condom use

Time Frame: 2 years

number of sexual partners

Time Frame: 2 years

Secondary Outcomes

  • knowledge and attitudes about substances and sex(2 years)
  • healthy leisure attitudes/behaviors(2 years)
  • levels of inter- and intrapersonal skills(2 years)

Study Sites (1)

Loading locations...

Similar Trials