Correlation of Vitamin B12 with blood clotting in COVID-19 patients

Not yet recruiting

Conditions: Coronavirus as the cause of diseases classified elsewhere,

Registration Number: CTRI/2021/02/030946

Lead Sponsor: GCS Medical College Hospital and Research Centre

Brief Summary: Aims- To compare Vitamin B12 levels and D-dimer levels of COVID 19 positive patientsTo establish, if any, correlation between Vitamin B12 deficiency and increased thrombosis (by means of D-Dimer) in the study population

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

1.All patients who are COVID-19 positive by either COVID-19 RTPCR test or COVID-19 rapid antigen test or HRCT chest suggestive of active COVID-19 infection (CORADS III AND ABOVE) 2.All genders 3.Age above 18 years 4.Patients willing to give consent for this study.

Exclusion Criteria

1.Patients who are COVID-19 negative 2.Patients who have taken Vitamin B12 supplements 3.Patients who might have raised D-Dimer due to other known causes; e.g. heart disease, prolonged bed rest, post surgical, etc 4.Pregnant and lactating women 5.Age <18 years 6.Patients not willing to give consent for this study.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To measure baseline Vitamin B12 levels in COVID19 positive patients	2 months
2.To measure baseline D Dimer levels in these patients	2 months
3.To measure maximum D Dimer levels in these patients through the course of hospital stay	2 months
4.To analyse following in the study population:	2 months
Duration of hospital stay	2 months
Need for oxygen support	2 months
Need for anticoagulation	2 months
Clinical outcome(recovered/expired)	2 months

Secondary Outcome Measures

Name	Time	Method
To compare thrombotic events in persons with Vitamin B12 deficiency and in those with normal levels	2 months

Trial Locations

Locations (1): GCS Medical College, Hospital and Research Centre
🇮🇳
Ahmadabad, GUJARAT, India
GCS Medical College, Hospital and Research Centre
🇮🇳Ahmadabad, GUJARAT, India
Dr Karmay Shah
Principal investigator
07966048028
karmay.shah@yahoo.co.in