Mediation Role of Perioperative Electroencephalogram Frontal Alpha Asymmetry to Pediatric Emergence Delirium
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- The peak PAED score
研究概览
简要总结
This study aimed to investigate whether the association between the preoperative anxiety level and emergence delirium involves EEG frontal alpha asymmetry in pediatric patients undergoing ophthalmic surgery under general anesthesia. The investigators hypothesized that EEG frontal alpha asymmetry contributes a significant portion of the preoperative anxiety - emergence delirium association in pediatric patients. Mediation analysis will be performed to estimate the relationships between preoperative anxiety of children (modified Yale Preoperative Anxiety Scale (mYPAS)), EEG frontal alpha asymmetry, and emergence delirium (Pediatric Assessment of Emergence Delirium (PAED) scale).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children aged 2-8 year
- •Children with an American Society of Anesthesiologists (ASA) physical status of I-II
- •Children who are scheduled to undergo elective ophthalmological requiring general anesthesia
排除标准
- •Emergency surgery
- •Patients with developmental delays
- •Patients with neurological or psychiatric diseases associated with symptoms of agitation, anxiety, attention deficit, sleep disturbances
- •Patients with autism
- •Patients with a recent history (within one month) of receiving general anesthesia
- •Patients with congenital or genetic diseases that may influence brain development
结局指标
主要结局
The peak PAED score
时间窗: After the completion of surgery, during the PACU stay. PAED score will be measured every 10 minutes during the PACU stay.
The peak PAED score is the primary outcome variable for mediation analysis
次要结局
未报告次要终点
研究者
Young Song
Professor
Gangnam Severance Hospital