Mediation Role of Perioperative Electroencephalogram Frontal Alpha Asymmetry to Pediatric Emergence Delirium
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Emergence Delirium
- Sponsor
- Gangnam Severance Hospital
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- The peak PAED score
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This study aimed to investigate whether the association between the preoperative anxiety level and emergence delirium involves EEG frontal alpha asymmetry in pediatric patients undergoing ophthalmic surgery under general anesthesia. The investigators hypothesized that EEG frontal alpha asymmetry contributes a significant portion of the preoperative anxiety - emergence delirium association in pediatric patients. Mediation analysis will be performed to estimate the relationships between preoperative anxiety of children (modified Yale Preoperative Anxiety Scale (mYPAS)), EEG frontal alpha asymmetry, and emergence delirium (Pediatric Assessment of Emergence Delirium (PAED) scale).
Investigators
Young Song
Professor
Gangnam Severance Hospital
Eligibility Criteria
Inclusion Criteria
- •Children aged 2-8 year
- •Children with an American Society of Anesthesiologists (ASA) physical status of I-II
- •Children who are scheduled to undergo elective ophthalmological requiring general anesthesia
Exclusion Criteria
- •Emergency surgery
- •Patients with developmental delays
- •Patients with neurological or psychiatric diseases associated with symptoms of agitation, anxiety, attention deficit, sleep disturbances
- •Patients with autism
- •Patients with a recent history (within one month) of receiving general anesthesia
- •Patients with congenital or genetic diseases that may influence brain development
Outcomes
Primary Outcomes
The peak PAED score
Time Frame: After the completion of surgery, during the PACU stay. PAED score will be measured every 10 minutes during the PACU stay.
The peak PAED score is the primary outcome variable for mediation analysis