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Clinical Trials/NCT04903743
NCT04903743
Unknown
Not Applicable

ULTRASOUND GUIDED POPLITEAL SCIATIC NERVE BLOCK USING BUPIVACAINE ALONE OR COMBINED WITH MAGNESIUM SULFATE FOR DIABETIC FOOT SURGERIES

Alexandria University1 site in 1 country50 target enrollmentJanuary 10, 2021

Overview

Phase
Not Applicable
Intervention
bupivacaine
Conditions
Diabetic Patient
Sponsor
Alexandria University
Enrollment
50
Locations
1
Primary Endpoint
duration of postoperative analgesia
Last Updated
4 years ago

Overview

Brief Summary

Popliteal Sciatic nerve block is a regional technique that provides safe and reliable perioperative anesthesia and analgesia of lower leg and foot used in diabetic patients. Different additives have been used with local anaesthetics to achieve dense and prolonged block. Magnesium sulfate possesses analgesic properties owing to its effect on NMDA receptors.

Registry
clinicaltrials.gov
Start Date
January 10, 2021
End Date
July 10, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

rehab zayed

Assisstant Professor of Anesthesia

Alexandria University

Eligibility Criteria

Inclusion Criteria

  • (ASA) II or III
  • scheduled for diabetic foot surgeries.

Exclusion Criteria

  • Patients who refused the anaesthetic technique,
  • whose BMI ≥ 35 kg/ m2,
  • unable to properly describe postoperative pain to investigator (dementia, delirium, psychiatric and neurological disorders),
  • patients with coagulopathy, skin infection at the site of injection,
  • preoperative use of opioid or non-steroidal anti-inflammatory drugs,
  • allergy or contraindication to studied medication

Arms & Interventions

group B

28ml of 0.25% bupivacaine and 2ml normal saline

Intervention: bupivacaine

group BM

received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.

Intervention: bupivacaine

group BM

received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.

Intervention: magnesium sulfate

Outcomes

Primary Outcomes

duration of postoperative analgesia

Time Frame: 24 hours

evaluate the effects of adding magnesium sulfate to bupivacaine versus bupivacaine alone in popliteal sciatic nerve block with ultrasound guidance for diabetic foot surgeries as regards the duration of postoperative analgesia

Study Sites (1)

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