ULTRASOUND GUIDED POPLITEAL SCIATIC NERVE BLOCK USING BUPIVACAINE ALONE OR COMBINED WITH MAGNESIUM SULFATE FOR DIABETIC FOOT SURGERIES
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- duration of postoperative analgesia
研究概览
简要总结
Popliteal Sciatic nerve block is a regional technique that provides safe and reliable perioperative anesthesia and analgesia of lower leg and foot used in diabetic patients. Different additives have been used with local anaesthetics to achieve dense and prolonged block. Magnesium sulfate possesses analgesic properties owing to its effect on NMDA receptors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(ASA) II or III
- •scheduled for diabetic foot surgeries.
排除标准
- •Patients who refused the anaesthetic technique,
- •whose BMI ≥ 35 kg/ m2,
- •unable to properly describe postoperative pain to investigator (dementia, delirium, psychiatric and neurological disorders),
- •patients with coagulopathy, skin infection at the site of injection,
- •preoperative use of opioid or non-steroidal anti-inflammatory drugs,
- •allergy or contraindication to studied medication
研究组 & 干预措施
group B
28ml of 0.25% bupivacaine and 2ml normal saline
干预措施: bupivacaine (Drug)
group BM
received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.
干预措施: bupivacaine (Drug)
group BM
received 28 ml of 0.25% bupivacaine and 2 ml magnesium sulfate 10%.
干预措施: magnesium sulfate (Drug)
结局指标
主要结局
duration of postoperative analgesia
时间窗: 24 hours
evaluate the effects of adding magnesium sulfate to bupivacaine versus bupivacaine alone in popliteal sciatic nerve block with ultrasound guidance for diabetic foot surgeries as regards the duration of postoperative analgesia
次要结局
未报告次要终点
研究者
rehab zayed
Assisstant Professor of Anesthesia
Alexandria University