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A Comparison of Anatomically Aligned Versus Conventional in Unilateral Total Knee Arthroplasty

Not Applicable
Conditions
Knee Osteoarthritis
Anatomically Aligned Total Knee Arthroplasty
Interventions
Device: Total knee arthroplasty implant
Registration Number
NCT04181528
Lead Sponsor
The Catholic University of Korea
Brief Summary

Total knee arthroplasty(TKA) is a successful orthopedic surgery with excellent clinical outcome and survival. However, there are concerns about patient satisfaction in previous reports, and dissatisfaction rate of 15-30% is reported in clinical outcomes(PROMs) of some studies. Therefore, for improving the patient's outcome and satisfaction after total knee arthroplasty, it is necessary to change the design of the conventional total knee arthroplsaty implant. The knee is a joint structure with several dynamic functions, and not only the skeletal structure but also the soft tissue balance plays an important role in the function of the knee joint. New implants are being developed to overcome the limitations of conventional TKA implant, including the Journey II Bi-cruciate substituting total knee system (JII-BCS; Smith \& Nephew). JII-BCS implant has normal articular geometry, more anatomical femoral shape, lateral tibial convex geometry, and asymmetrical tibial plateau, anterior and posterior cams, which has been shown in experimental studies to produce nearly normal knee movement by reproducing the actual normal anatomical alignment in vivo. The clinical results of the kinematic effects of this anatomcally aligned change are insufficient, and there is also a lack of comparative studies with conventional total knee arthroplasty implant. The purpose of this study is to compare outcomes between anatomically aligned TKA(JII-BCS) and conventional TKA(Legion total knee system, Smith \& Nephew). This study is a randomized controlled study in patients undergoing unilateral total knee arthroplasty. A patient will undergo unilateral TKA with anatomically aligned or conventional TKA implant. The implant is determined using a random number table. Radiologic parameter, patients preference and clinical results was investigated in patients who received unilateral TKA during minimum 2 year follow up.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Patients for bilateral total knee arthroplasty
  • having medicare insurance
Exclusion Criteria
  • Rheumatoid arthritis
  • Other inflammatory arthritis
  • Crystal-induced arthritis
  • Septic arthritis
  • Neuropsychiatric patients
  • Previous knee operation history
  • Neuropsychiatric patients
  • Patients with preoperative severe limitation of motion (Flexion contracture ≥ 20, range of motion ≤ 90)
  • Patients with preoperative severe defomity of knee alignment (Varus or valgus angle ≥ 15)
  • Severe obese patients (BMI ≥ 40)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Conventaional total knee arthroplastyTotal knee arthroplasty implantUse conventional TKA implant (Legion total knee system, JII-BCS, Smith \& Nephew) in patients undergoing unilateral TKA
Anatomically aligned total knee arthroplastyTotal knee arthroplasty implantUse anatomically aligned TKA implant (Journey II Bi-cruciate substituting total knee system, JII-BCS, Smith \& Nephew) in patients undergoing unilateral TKA
Primary Outcome Measures
NameTimeMethod
Change in Western Ontario and McMaster Universities Index(WOMAC index)hange from baseline score to score of postoperative1 year
Secondary Outcome Measures
NameTimeMethod
Change in Range of MotionChange from baseline Range of Motion at postoperative1 year
Change in Knee Society ScoreChange from baseline score to score of postoperative1 year
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