Prospective, randomized, placebo controlled trial to evaluate the efficacy of transcutaneous stimulation of n. tibialis posterior in treatment of idiopathic overactive bladder - TNT-Trial

niversitätsklinikum Münster0 个研究点目标入组 116 人开始时间: 2021年10月4日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Idiopathic overactive bladder
•Age 18 to 70 years
•Ability to give consent
•Oral drug treatment of OAB should be discontinued 4 weeks before the start of treatment or continued for the duration of the study

•Children <18 LJ.
•Age> 80.LJ
•Taking psychotropic drugs, antiepileptics, antidepressants
•Interruption of antimuscarinergics within the last 4 weeks before entering the study
•Presence of a any pacemaker
•recent other neuromodulative procedures (sacral neuromodulation, percutaneous tibial nerve stimulation) Sacral neuromodulation
•recent Injection treatment with botox in the detrusor
•Neurogenic genesis of urinary symptoms (e.g. apoplex, multiple sclerosis, Parkinson disease, paraplegia)
•? obstructive micturition complaints
•TRUS: prostate size> 40 cc, uroflowmetry: maximum urine flow <15 ml / s
•? urogenital descensus> 2 °, any symptomatic urogenital descensus
•Stress incontinence> 1 °
•Bladder pain syndrome / interstitial cystitis
•any history of bladder tumor
•recurrent urinary tract infections (> 3 / year or> 2 / half year)
•anatomical abnormalities of the urinary bladder and urethra such as Bladder diverticulum, bladder wall thickening (> 2.5mm with 250 ml bladder filling), urethral stricture
•residual urine over 20% of the micturition volume or> 100 ml

发起方

niversitätsklinikum Münster