DEXMEDETOMIDINE ADJUVANT TO LOCAL ANAESTHESIA FOR PERIBULBAR BLOCKS IN RETINAL SURGERY
试验速览
- 阶段
- 3 期
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- onset, duration of the motor and sensory block
研究概览
简要总结
During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl .
The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 40 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients
- •Going for elective vitreoretinal surgery.
排除标准
- •History of coagulation abnormalities.
- •Allergy to local anesthetics.
- •Cardiac, hepatic or renal failure,
- •Chronic clonidine or analgesic therapy.
- •One-eyed patients
研究组 & 干预措施
5 micron dex arm
干预措施: DEXMEDETOMIDINE (Drug)
10 micron dex arm
干预措施: DEXMEDETOMIDINE (Drug)
结局指标
主要结局
onset, duration of the motor and sensory block
时间窗: 10 minutes from injection
A block was considered satisfactory when complete akinesia occurred. In the absence of complete akinesia in any direction after 10 min, supplementary anesthesia given by a further injection of 2-4 ml of the test solution in the same manner as given before. Calculate the number of patients needed supplemental block were. The surgeon assessed the duration of surgery anesthesia and akinesia. Intraocular pressure measured before block, immediately after block and before surgical procedures
次要结局
- observe the adverse effects of Dexmedetomidine(during and after surgery)
研究者
Marwan Abouammoh
Associate professor
King Saud University