Anti-Mullerian Hormone Levels Before and After an Open Myomectomy

Terminated

• Conditions: Anti-Mullerian Hormone

• Registration Number: NCT01723085
• Lead Sponsor: Clinique Ovo

Brief Summary

Anti-Mullerian hormone (AMH) is a marker for ovarian reserve. It is well known that ovarian surgery for endometriosis lowers Anti-Mullerian hormone, but little is known for other surgeries. We seek to investigate the hormone variations before and after an open myomectomy.

Hypothesis: Anti-Mullerian hormone levels drop following surgery but return to normal levels in a few months

Detailed Description

Not available

Study Timeline

• Study Start: 2012-03
• Study First Submitted: 2012-11-05
• Study First Submitted QC: 2012-11-05
• Study First Posted: 2012-11-07
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Status Verified: 2018-07
• Last Update Submitted: 2018-07-27
• Last Update Posted: 2018-07-30

Recruitment & Eligibility

• Status: TERMINATED
• Sex: Female
• Target Recruitment: 21

Inclusion Criteria

• 18 to 42 years old
• Requiring open myomectomy for any indication

Exclusion Criteria

• Incapable of informed consent
• Use of hormonal contraception or Gonadotropin-releasing hormone agonists in the past 3 months
• Woman over 42 years old
• Post-menopause women
• Positive B-human chorionic gonadotropin the day of surgery
• Ovarian surgery (at the same time)
• Pre-operative AMH below 0.3 ng/mL

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anti-Mullerian Hormone levels variation	6 months	Anti-Mullerian Hormone levels before and 6 months after surgery

Trial Locations

Locations (1)

Hopital Saint-Luc; 🇨🇦 Montreal, Quebec, Canada