Is repeated laser treatment effective in intraocular pressure (IOP) reduction?

Completed

• Conditions: Glaucoma; Eye Diseases

• Registration Number: ISRCTN67927615
• Lead Sponsor: St Eriks Eye Hospital (Sweden)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-03-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Patients suffering from glaucoma or Ocular Hypertenstion (OHT)
1.1. Primary open angle glaucoma (POAG) - open angle defined as > grade II (Shaffer classification: scale 0-IV) assessed by gonioscopy
1.2. Pigmentary and pseudoexfoliative glaucoma
1.3. OHT to be treated with SLT 2 both with and without eye-drops.
2. If both eyes must be treated just one will be selected at random.
3. Older than 18 years, no upper age limit
4. Men and women

Exclusion Criteria

1. Patients treated with cortisone or immunosuppressive drugs
2. Patients suffering from ocular or systemic inflammatory diseases
3. Patients with Possner-Schlossman syndrome
4. Patients that cannot be treated with SLT due to eye?s characteristics (shallow anterior chamber) or bad collaboration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IOP after repeated SLT in the same area against repeated SLT treatment in adjacent areas. <br>IOP will be measured with the Goldmann applanation tonometry (GAT) at base line (before treatment) and then 1, 3, 6 and 12 months after treatment.

Secondary Outcome Measures

Name	Time	Method
1. Gender?s influence on IOP<br>2. Age?s influence on IOP<br>3. Pseudoexfoliation?s influence on IOP<br>4. Inflammation measurements using a slit-lamp and according to the international classification of the Standardization of Uveitis Nomenclature (SUN) Working Group