Topical Dexamethasone Tube Soaking for Prevention of Postoperative Sore Throat (POST) Following Endotracheal Intubation for Laparoscopic Cholecystectomy: A Randomized Controlled Trial
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- Incidence of post operative sore throat
研究概览
简要总结
The goal of this clinical trial is to learn if topical application of dexamethasone will prevent sore throat caused by endotracheal intubation in healthy patients undergoing elective surgery. The main question it aims to answer is:
• Does soaking the endotracheal tube in steroid solution before intubation lower the incidence of postoperative sore throat? Researcher will compare dexamethasone-soaked endotracheal tube to placebo (normal saline-soaked endotracheal tube) to see if topical steroid application in this way reduces development of sore throat.
Participants will be:
- Intubated with an endotracheal tube, that was either soaked in normal saline or dexamethasone solution, at induction of general anesthesia prior to undergoing elective cholecystectomy
- Interviewed by the researcher 24 hours after their surgery to assess if they experienced any throat soreness
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing general anesthesia requiring ETT insertion during elective laparoscopic cholecystectomy.
- •ASA I & ASA II patients
- •Patients consenting to be a part of the study
排除标准
- •Patients having diabetes mellitus
- •Patients with suspected or incidental difficult Intubation
研究组 & 干预措施
Dexamethasone group
Participants intubated with endotracheal tube soaked in dexamethasone solution
干预措施: Steroid Drug (Drug)
Normal saline group
Participants intubated with endotracheal tube soaked in normal saline
干预措施: Normal (0.9%) saline (Drug)
结局指标
主要结局
Incidence of post operative sore throat
时间窗: Within 24 hours of surgery
Proportion of patients who develop sore throat after surgery
次要结局
未报告次要终点
研究者
Mariam Niaz
Post Graduate Trainee
KRL Hospital, Islamabad