Albumin Use in Burn Patients

Completed

• Conditions: Burns

• Registration Number: NCT00609414
• Lead Sponsor: University of North Carolina, Chapel Hill

Brief Summary

This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

Detailed Description

While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.

Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.

Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2008-01-24
• Study First Submitted QC: 2008-01-24
• Study First Posted: 2008-02-07
• Primary Completion: 2008-10
• Study Completion: 2008-10
• Status Verified: 2011-04
• Last Update Submitted: 2011-04-15
• Last Update Posted: 2011-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 460

Inclusion Criteria

• Burn Injury, with and without inhalation injury

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Exclusion Criteria

• <20% Total Body Surface Area Burned
• Comfort care only for the burn injury

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (12)

Joseph M Still Research Foundation Inc and Doctors Hospital of Augusta; 🇺🇸 Augusta, Georgia, United States

Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre; 🇨🇦 Toronto, Ontario, Canada

Shriners Hospitals for Children; 🇺🇸 Cincinnati, Ohio, United States

Regions Hospital Burn Center; 🇺🇸 St. Paul, Minnesota, United States

Bothin Burn Center, University of Kansas Hospital; 🇺🇸 Kansas City, Kansas, United States

University of Utah Hospitals Burn Center; 🇺🇸 Salt Lake City, Utah, United States

Bothin Burn Center, Saint Francis Memorial Hospital; 🇺🇸 San Francisco, California, United States

North Carolina Jaycee Burn Center, University of North Carolina Hospitals; 🇺🇸 Chapel Hill, North Carolina, United States

Shands at the University of Florida Burn Center; 🇺🇸 Gainesville, Florida, United States

Paul and Carol David Foundation Burn Institute, Akron Children's Hospital; 🇺🇸 Akron, Ohio, United States

Arizona Burn Center, Maricopa Medical Center; 🇺🇸 Phoenix, Arizona, United States

Oregon Burn Center, Legacy Health System; 🇺🇸 Portland, Oregon, United States