Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment

Completed

• Conditions: Vitamin A Deficiency

• Registration Number: NCT01559766
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency. However, there is little information on the vitamin A requirement of Chinese children. In the present study, about 400 children aged between 4 and 9 years old in a kindergarten and an elementary school of Shiyan City were screened before admission by questionnaire and anthropometric measurement. The vitamin A status of children was assessed by serum vitamin A level, relative dosage reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in young children was determined on the basis of dietary vitamin A intakes in Children with adequate vitamin A level.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07
• Primary Completion: 2010-07
• Study Completion: 2010-09
• Status Verified: 2012-03
• Study First Submitted: 2012-03-19
• Study First Submitted QC: 2012-03-20
• Last Update Submitted: 2012-03-20
• Study First Posted: 2012-03-21
• Last Update Posted: 2012-03-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 403

Inclusion Criteria

• well-nourished children with normal serum retinol(>=1.40umol/L)

Exclusion Criteria

• ongoing or previous illnesses,
• having taken nutritional supplements within 3 months,
• positive results in the fat absorption test or parasite test,
• increased level of CRP (> 8 mg/L), or
• lower serum level of retinol (< 1.40 umol/L)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Shiyan Centre for Disease Control and Prevention; 🇨🇳 Shiyan, Hubei, China