Comparison of Pheniramine and Hyoscine for management of post operative catheter related bladder discomfort after general anaesthesia.

Not Applicable

Completed

• Conditions: Health Condition 1: O- Medical and SurgicalHealth Condition 2: O- Medical and Surgical

• Registration Number: CTRI/2021/08/035651
• Lead Sponsor: Dayanand Medical college and Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-05-25
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

1.Adult male patient between 25-55 years of age posted for elective non- urological surgeries under general anaesthesia.

2.American Society of Anaesthesiologist(ASA) Class I-II.

Exclusion Criteria

1.Clinical evidence of previous lower urinary system diseases needing medical or surgical intervention (such as prostate diseases or urethral stricture),

2.History or current evidence of urinary tract infection (UTI).

3.Bladder outlet obstruction, overactive bladder (urination frequency > 3 times/night or > 8 times in 24 h)

4.Patients already on alpha 1 adrenergic antagonists like tamsulosin.

5.Any difficulty or resistance encountered during catheterization.

6.Morbid obesity (body mass index over 40).

7.Chronic renal failure.

8.History of ischemic heart disease, myocardial infarction, hepatic or psychiatric disease.

9.History of substance abuse, chronic pain or gabapentin use.

10.History of neurologic disease like stroke, parkinsonism, alzeihemerâ??s.

11.History of Bronchial asthma or thyroid disease.

12. History of narrow angle glaucoma.

13.Patients with catheter in-situ before shifting to operating room.

14.History of drug allergy to Diclofenac, Pheniramine and Hyoscine

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be measured as reduction in severity of CRBD.Timepoint: The patients will be observed at 30 mnutes ,then at 1 hour then every hourly till 6 hours for CRBD.

Secondary Outcome Measures

Name	Time	Method
The secondary outcome will be measured as dose and frequency of post-operative analgesic (tramadol) used and adverse effects.Timepoint: 6 hours