A study to determine possible etiological links between biological factors and dentofacial phenotypes
Recruiting
- Conditions
- Patients with dentofacial phenotypes
- Registration Number
- DRKS00034466
- Lead Sponsor
- niversitätsklinikum Bonn, Poliklinik für Kieferorthopädie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1050
Inclusion Criteria
The informed patient and, in the case of minors, their legal guardians must have consented to participate in the study. The diagnostic documents which are relevant for the individual examinations (outcomes) must be available and have been prepared as part of a medically indicated dental-orthodontic diagnosis and treatment. An exception is the saliva sample to be obtained as part of the study. In addition, only systemically healthy patients or patients with mild systemic and well-controlled diseases should be included in the study.
Exclusion Criteria
Patients with serious systemic diseases and known genetic and non-genetic syndromes as well as traumas or operations in the head and neck area
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Evaluation of the molecular and clinical aspects related to the phenotypes of normal tooth development and the phenotypes of developmental tooth changes<br>- Investigation of the clinical and genetic factors that influence the tooth age<br>- Investigation of the molecular factors and clinical factors involved in the development of adverse side effects of orthodontic treatment.
- Secondary Outcome Measures
Name Time Method not applicable