临床试验/NCT03969550

NCT03969550已完成不适用

Do CCR5 Antagonists Improve the Overall Survival of Patients With AIDS-related Progressive Multifocal Leucoencephalopathy?

Fondation Ophtalmologique Adolphe de Rothschild0 个研究点目标入组 34 人开始时间: 2008年1月最近更新: 2019年5月31日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Fondation Ophtalmologique Adolphe de Rothschild
入组人数: 34
主要终点: Overall survival (OS)

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

Progressive multifocal leucoencephalopathy (PML) is a demyelinating disease caused by John Cunningham virus (JCV) reactivation. Numerous molecules have been overstated because there were inaccurately tested in non-rigorous clinical trial.

The objective is to draw lessons from repeatedly false hopes of unconfirmed PML treatments that might contribute to prescribing ineffective drugs on claimed efficacy in case reports or small series and by failing to respect the need for clinical trial evaluation before authorizing their widespread use.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Retrospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients with AR-PML
•Diagnosed between January 2008 and December 2015
•Followed in one of the four University Hospitals' Infectious Diseases Departments

排除标准

未提供

结局指标

主要结局

Overall survival (OS)

时间窗: 8 years

次要结局

未报告次要终点

研究者

发起方

Fondation Ophtalmologique Adolphe de Rothschild

申办方类型

Network

责任方

Sponsor

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