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Clinical Trials/NCT07630896
NCT07630896Not yet recruitingPhase 4

Postoperative Prednisone Regimen in TKA and Its Effect on Continuous Glucose Levels

Columbia University1 site in 1 country104 target enrollmentStarted: July 1, 2026Last updated:
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Conditions

Trial Snapshot

Phase
Phase 4
Status
Not yet recruiting
Enrollment
104
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Undergoing Primary Unicompartmental Knee Arthroplasty or Total Hip Arthroplasty
  • •Age 18 and above

Exclusion Criteria

  • •Steroid therapy
  • •Narcotic use within past 3 months
  • •History of corticosteroid intolerance
  • •Pregnancy
  • •Uncontrolled diabetes
  • •Doesn't own smart phone
  • •Drop Criteria:
  • •- 2nd dose of IV dexamethasone

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Roshan P. Shah

Russell A. Hibbs Associate Professor of Orthopedics in Orthopedic Surgery and in Surgery

Columbia University

Study Sites (1)

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