Comparison of the Efficacy of Intraocular Lens Optic Capture and In-the-bag Implantation Over 1 Year in Children With Congenital Cataract

• Conditions: Intraocular Lens Implantation; Congenital Cataract; Optic Capture
• Interventions: Procedure: primary or secondary intraocular lens implantation surgery

• Registration Number: NCT05275764
• Lead Sponsor: Wenzhou Medical University

Brief Summary

Approximately 30 eyes with congenital cataract who underwent primary or secondary intraocular lens implantation surgery at Zhejiang Eye Hospital from March 2018 to December 2020 were enrolled. According to the implantation method of IOL, patients were devided into the optic capture group and the endocapsular group. And through the clinical parameters of postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), IOL position and whether appear visual axis opacity to compare the outcome of the 2 IOL implantation methods.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-01
• Study First Submitted: 2022-02-19
• Status Verified: 2022-03
• Study First Submitted QC: 2022-03-10
• Last Update Submitted: 2022-03-10
• Study First Posted: 2022-03-11
• Last Update Posted: 2022-03-11
• Primary Completion: 2022-06-30
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Children aged 1 to 10 years diagnosed with congenital cataract
• underwent I / II IOL implantation in our hospital
• corneal diameter more than 9mm
• Good compliance

Exclusion Criteria

• Patients with other ocular or systemic diseases
• patients whose IOL cannot be implanted in or after the capsule due to ocular conditions
• Children with a history of other ocular surgery
• Low compliance

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
endocapsular group	primary or secondary intraocular lens implantation surgery	IOL was placed in the bag
optic capture group	primary or secondary intraocular lens implantation surgery	IOL optic was captured through the posterior continuous curvilinear capsulorhexis

Primary Outcome Measures

Name	Time	Method
IOL position	through study completion, an average of 1 year	The horizontal and vertical inclination of IOL
BCVA	through study completion, an average of 1 year	best corrected visual acuity

Trial Locations

Locations (1)

Eye Hospital of Wenzhou Medical College; 🇨🇳 Wenzhou, Zhejiang, China