NCT04772846Unknown1 期
Adjuvant Chloroquine to the Conventional Treatment for Glioblastoma.
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Survival duration after surgery
研究概览
简要总结
Adjuvant chloroquine to the conventional treatment for glioblastoma; A randomized, single-blind, placebo-controlled, phase I/II trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Care Provider)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histologically confirmed glioblastoma Adequate hematologic, hepatic, and renal function Karnofsky performance status score ≥ 70% Life expectancy ≥ six weeks
排除标准
- •Abnormal severe un-controlled medical conditions
研究组 & 干预措施
Chloroquine group
Experimental
干预措施: Oral tablet (Drug)
Placebo drug group
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
Survival duration after surgery
时间窗: Three years
次要结局
- End-point evaluation, survival at three years(Three years)
研究者
Mohammed A. Azab
Department of Neurosurgery
Cairo University
研究点 (1)
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