Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss
Not Applicable
Recruiting
- Conditions
- Blood Loss
- Interventions
- Drug: local tranexamic acid injectionOther: local normal saline injection to cervix
- Registration Number
- NCT04760301
- Lead Sponsor
- Meir Medical Center
- Brief Summary
Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation
- Detailed Description
This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy.
The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; local 1gr tranexamic acid diluted in 10 ml saline and local 10 ml saline at the beginning of surgery.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
- 20-90 years old female patients going through vaginal hysterctomy
Exclusion Criteria
- massive bleeding during operation due to major vessles injury
- known coagulopathies
- sensitivity to tranexamic acid
- medical need in tranexamic acid administration during operation due to bleeding
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description local tranexamic acid injection to cervix local tranexamic acid injection 1 gr of Tranexamic acid diluted in 10 ml saline local normal saline injection to cervix local normal saline injection to cervix 20 ml of saline
- Primary Outcome Measures
Name Time Method Blood loss during operation - measure in ml End of surgery At the end of the surgery, surgeon will measure the blood in the suction can
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Meir Medical Center
🇮🇱Kfar Saba,, Israel
Meir medical center
🇮🇱Kfar Saba, Israel