Comparison of optic nerve perfusion after pan retinal photocoagulation (PRP) versus anti vascular endothelial growth factor (antiVEGF) injection for treatment of high risk proliferative diabetic retinopathy(PDR)

Not Applicable

• Conditions: Eye Diseases; Paediatrics

• Registration Number: PACTR202206535473146
• Lead Sponsor: Ain shams university hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-05-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Other
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

? Naive high risk PDR (neovascularization on disc (NVD) more than 1/3 disc area or any NVD with vitreous hemorrhage)
? clear media

Exclusion Criteria

? patients with media opacity
? other retinal and optic nerve diseases rather than diabetic retinopathy
? anti VEGF or steroid intravitreal injection
? previous PRP
? tractional retinal detachment
? glaucoma or any form of optic neuropathy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
comparing peri papillary vascular density after PRP and anti VEGF (Ranizumab)

Secondary Outcome Measures

Name	Time	Method
1. Visual field change (mean deviation and pattern standard deviation)<br>2. macular capillary density<br>3. visual acuity<br>4. Neovascular area on disc (NVD area) if possible