Effect of Eliminating Routine Gastric Residual Volume Monitoring on Ventilator-associated Events in Patients Receiving Enteral Feeding
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 160
- 主要终点
- eliminating gastric residual volume monitoring on ventilator associated events
研究概览
简要总结
The aims of this study are to investigate the effect of eliminating routine GRV monitoring on VAEs in patients receiving MV and early EF, Determine the effect of eliminating routine GRV monitoring on nutritional adequacy in patients receiving MV and early EF and evaluate the effect of eliminating routine GRV monitoring on feeding intolerance in patients receiving enteral feeding.
详细描述
Early enteral nutrition (EN) is consistently recommended as first line nutrition therapy in critically ill patients since it favorably alters outcome, providing both nutrition and non-nutrition benefits. However, critically ill patients receiving mechanical ventilation (MV) are at risk for regurgitation, pulmonary aspiration, and eventually ventilator-associated pneumonia (VAP). EN may increase these risks when gastrointestinal (GI) dysfunction is present. Gastric residual volume (GRV) is considered a surrogate parameter of GI dysfunction during the progression of enteral feeding in the early phase of critical illness and beyond. About 62% of critically ill patients receive enteral nutrition (EN) and in patients on MV, enteral feeding was connected to a threefold increase in the development of VAP.
A new surveillance definition of ventilator-associated events (VAE) was introduced by the National Healthcare Safety Network (NHSN) in 2013 to identify patients who develop complications of MV. It outlines the various events in a step-by-step fashion, beginning with ventilator-associated complications (VAC), moving on to infectious complications (IVAC), and finally VAP. According to the NHSN, VAEs occur within 9% to 40% of mechanically ventilated patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (aged≥18 years)
- •Newly admitted mechanically ventilated patients who are attached to a mechanical ventilator for at least 48 hours.
- •Starting enteral nutrition via a nasogastric tube within 36 hours after intubation.
排除标准
- •Abdominal surgery within the past month.
- •History of esophageal, duodenal, pancreatic, or gastric surgery.
- •Bleeding from the esophagus, stomach, or bowel.
- •Enteral nutrition via a jejunostomy or gastrostomy.
- •Pregnancy
结局指标
主要结局
eliminating gastric residual volume monitoring on ventilator associated events
时间窗: 3 month
use centers for disease control and prevention (CDC) calculators for evaluating VAE version 9.0 2021
次要结局
- eliminating gastric residual volume monitoring on nutritional adequacy(3 month)
- eliminating gastric residual volume monitoring on incidence of feeding intolerance indicators(3 month)
