The Effect of modified Stavudine and lamivudine containing regimen in antiretroviral therapy on clinical, immunological and virological outcomes in HIV-infected patients in Dar es Salaam, Tanzania. (STALEO TRIAL)

International Clinical Operations Health Research in Tanzania (ICOHRTA)0 个研究点目标入组 520 人开始时间: 2012年8月13日最近更新: 2023年5月29日

适应症

试验速览

暂无简介。

•¿HIV-infected as documented by positive HIV antibody test.
•¿Subject is at least 18 years of age at the day of the first HIV clinic visits.
•¿Able to give informed consent
•¿CD4+ T lymphocyte count less or equal to 350 cell/mm3 or those indicated for antiretroviral therapy by WHOstaging criterio
•¿Karnofsky score > 40.
•¿Willing and able to regularly attend the HIV clinic at the designated sites.
•¿Patient note exposed to antiretroviral drugs as determined by self reporting.
•¿Women with a negative urinary pregnancy during enrolment

•¿Women expected to bear a child during the study period as determined during initial assessment.
•¿A history of severe psychiatric disease such as psychosis, schizophrenia, depression,
•¿Patient with clinically confirmed neuropathy and lipodystrophy

发起方

International Clinical Operations Health Research in Tanzania (ICOHRTA)