Vestibular neuromodulation for the treatment of persistent pain: An open label case series

Dr Steven Miller0 个研究点目标入组 100 人开始时间: 2024年3月5日最近更新: 2024年3月11日

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•Patients with persistent pain (PP). This includes any pain condition that can present to a pain specialist, with the exception of spinal cord injury pain, visceral/abdominal/pelvic pain, and purely nociceptive musculoskeletal pain. A non- exhaustive list of the types of PP patients to be recruited includes those with: persistent neck pain, back pain, upper or lower limb pain, neuropathic pain (such as due to diabetes, chemotherapy, post-herpetic neuralgia, occipital neuralgia, trigeminal neuralgia), complex regional pain syndrome, failed back surgery syndrome (persistent post-spinal surgery pain syndrome), nociplastic pain with central sensitisation, post-stroke central pain syndrome (thalamic pain syndrome), and phantom limb pain.

•(i) Younger than 18 or older than 70 (simple precaution exclusion)
•(ii) Spinal cord injury pain, visceral/abdominal/pelvic pain, purely nociceptive pain (spinal cord injury patients did not appear to respond well to the CVS treatment in a previous study; visceral/abdominal/pelvic pain conditions are outside the scope of this study; purely nociceptive pain is unlikely to respond)
•(iii) Somatic symptom disorder with predominant pain (i.e., a primary psychiatric pain disorder) or significant abnormal illness behaviour/non-organic presentation features (psychiatric pain disorders are outside the scope of the study and abnormal illness behaviour features could complicate data interpretation)
•(iv) unstable medical condition (e.g. unstable cardiac or respiratory issues) (simple precaution exclusion)
•(v) epilepsy (simple precaution exclusion)
•(vi) brain injury, other than stroke with central pain being the targeted PP condition (simple precaution exclusion)
•(vii) currently pregnant (simple precaution exclusion)
•(viii) bipolar disorder, schizophrenia or other psychotic disorder (simple precaution exclusion and theoretical risk of exacerbating mood disorder symptoms)
•(ix) significant ear disease in the right ear (or left ear if considering left ear CVS) (avoids risk of worsening any significant ear condition through having water irrigated into the ear canal)

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