OKKO Health Hyperacuity, Contrast and Colour Game Validation in Age-related Macular Degeneration
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Contrast sensitivity
研究概览
简要总结
Smartphone apps have the potential to measure standard metrics of visual function. In addition, new tests may serve as digital biomarkers to detect early progression of disease, assess risk of developing disease or expand the patient's clinical picture. Smartphones are inherently advantageous to reduce the reliance on specialist bulky and costly equipment that currently only exists in specialist clinics. While there are some smartphone apps available for vision monitoring, very few have any clinical evidence to support reliability, validity and diagnostic accuracy.
The OKKO Health app (www.okkohealth.com) is a smartphone app available on Apple iOS and Android platforms, consisting of short games with applied vision science technology to measure visual function in an engaging way. The app has one game per function, each on average 1-2 minutes. There are 4 game modes available testing visual acuity, contrast sensitivity, colour sensitivity and hyperacuity. This study will aim to validate these measures of visual function against gold standard clinical tests.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants with AMD in at least one eye
- •Willing to travel to the clinic in Exmouth/Bristol
- •Able to hold and use a smartphone
排除标准
- •Significant ocular pathology other than AMD
- •Unable to provide written informed consent
结局指标
主要结局
Contrast sensitivity
时间窗: Day 1
Contrast sensitivity collected in the OKKO Health app and via Pelli Robson chart.
Colour sensitivity
时间窗: Day 1
Colour sensitivity collected in the OKKO Health app and via City University colour test/Mollon-Reffin colour vision test.
Visual acuity
时间窗: Day 1
Visual acuity collected in the OKKO Health app and via ETDRS chart
次要结局
- Visual distortion(Day 1)
- Optical coherence tomography (OCT)(Day 1)
