A randomized, parallel-group, multicenter clinical trial to evaluate the preventive effect on acute exacerbation of chronic obstructive pulmonary disease (COPD) with Carbocisteine (1500mg/day)
Not Applicable
- Conditions
- COPD
- Registration Number
- JPRN-C000000232
- Lead Sponsor
- Department of Respiratory Medicine Juntendo University, School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
1. Intolerance for Carbocisteine 2. Use of mucolytic agents within one month prior to beginning of the study 3. Use of antibiotics at the beginning of the study 4. Bronchiectasis, pneumonia, interstitial lung disease, tuberculosis 5. Carcinoma 6. Previous lung transplant or lung volume reduction surgery 7. Pregnant or breastfeeding 8. Attendance in the other study within 3 months prior to the beginning of the study 9. Underlying severe disease
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of exacerbations
- Secondary Outcome Measures
Name Time Method