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Clinical Trials/ISRCTN76437720
ISRCTN76437720
Active, Not Recruiting
N/A

A randomised controlled feasibility trial of a novel polyvinylideneflouride (PVDF) mesh (DYNAMesh-hIatus) Cruroplasty versus suture only repair of large hiatus hernia

Portsmouth Hospital NHS Trust0 sites40 target enrollmentNovember 19, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Surgical repair of hiatus hernia
Sponsor
Portsmouth Hospital NHS Trust
Enrollment
40
Status
Active, Not Recruiting
Last Updated
6 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
November 19, 2018
End Date
November 1, 2023
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Portsmouth Hospital NHS Trust

Eligibility Criteria

Inclusion Criteria

  • 1\. NHS patients undergoing:
  • 1\.1\. Elective laparoscopic repair of large hiatus hernia (\>5 cm in size)
  • 1\.2\. Fundoplication for gastro\-oesophageal reflux disease
  • 2\. Fulfil criteria for keyhole surgery
  • 3\. Aged 18 years or older
  • 4\. Body mass index \<40 kg/m²
  • 5\. Able to provide written informed consent

Exclusion Criteria

  • 1\. Concomitant medical condition likely to shorten survival to less than 1 year
  • 2\. Previous hiatus hernia surgery
  • 3\. Active treatment for any cancer
  • 4\. Pregnancy
  • 5\. Contraindications to MRI for supplementary MRI study (can still be recruited into the study, but not for the MRI study at 1 year), including:
  • 5\.1\. Any metal implants
  • 5\.2\. Pacemaker
  • 5\.3\. Reveal devices

Outcomes

Primary Outcomes

Not specified

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