TCTR20230913003已完成不适用
Perilla seed oil as an adjunctive treatment with a statin improves lipid profiles in elderly: a post hoc data analysis.
Center of Excellence in Stroke, Thammasat University0 个研究点目标入组 182 人开始时间: 2023年9月13日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 182
研究概览
简要总结
In summary, perilla seed oil, particularly when combined with statin therapy, is promising for improving lipid profiles and might offer liver protection. While its omega-3 content and beneficial compounds are valuable, further research, including long-term studies, is needed to fully validate its clinical benefits in treating cardiovascular disease and related concerns.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 50 Years 至 90 Years(—)
- 性别
- All
入选标准
- •The patients were 50-90 years old and gained 10-23 scores measured by the Thai Mental State Examination (TMSE) or 7-20 scores measured by the Thai Montreal Cognitive Assessment (MoCA-Thai). They suffered from mild to moderate dementia based on the Diagnosis and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). They could recognize and communicate and gave written informed consent.
排除标准
- •They were found to have creatinine greater than 2 mg/dL on the recruitment day. Their laboratory results showed 2.5 times greater abnormal liver function than the upper normal limit. The patients had treatable causes of dementia, such as vitamin B12 deficiency, hypothyroidism, normal pressure hydrocephalus, and neuro-syphilis. They had bleeding disorders. They were receiving warfarin or taking supplements. They suffered from major depression. They were allergic to medicinal and herbal medicines.
研究者
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