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临床试验/NCT07604519
NCT07604519已完成不适用

Dose-Dependent Effects of Multi-Ingredient Supplementation on Physical Performance, Recovery, and Cognitive Function in Professional Football Players

Vizja University in Warsaw5 个研究点 分布在 3 个国家目标入组 97 人开始时间: 2026年6月14日最近更新:
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
97
试验地点
5

研究概览

简要总结

This randomized double-blind placebo-controlled trial will investigate the effects of multi-ingredient supplementation containing taurine, caffeine, and phosphatidylserine on physical performance, cognitive function, cognitive fatigue responses, recovery, sleep quality, and autonomic nervous system activity in elite male soccer players. Participants will complete a 14-day supplementation protocol and undergo football-specific performance, reaction-time, cognitive-fatigue, recovery, and sleep-related assessments before and after the intervention. The study aims to determine whether phosphatidylserine dose influences physical, cognitive, fatigue-related, and recovery-related outcomes when combined with taurine and caffeine.

详细描述

The planned study will be a randomized, double-blind, placebo-controlled trial designed as a continuation and extension of previous research on multi-ingredient supplementation in professional football players. The primary aim will be to investigate the dose-dependent effects of phosphatidylserine combined with taurine and caffeine under standardized football-specific training conditions and acute cognitive-fatigue conditions.

Approximately 80 professional male football players competing at national level will be randomly assigned to four groups: placebo, taurine + caffeine, taurine + caffeine + phosphatidylserine 300 mg, and taurine + caffeine + phosphatidylserine 600 mg. Importantly, caffeine and taurine doses will remain identical across all active supplementation groups in order to enable a more precise evaluation of the independent effects of phosphatidylserine.

Participants will complete a 14-day supplementation protocol and undergo baseline and post-intervention assessments including 30 m sprint performance, reaction time, cognitive-fatigue responses, football-specific GPS monitoring, fatigue-related performance decline, recovery-related variables, sleep monitoring, and autonomic nervous system activity assessment.

The study is expected to provide novel insights into the role of phosphatidylserine in football-specific performance, cognitive fatigue resistance, recovery, and neurophysiological responses in elite football players.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Inclusion Criteria:
  • Professional male football players aged 18-35 years
  • Regular participation in team training and competitive matches
  • Clinically healthy status confirmed prior to participation
  • Written informed consent provided

排除标准

  • Current musculoskeletal injury or illness
  • Chronic metabolic, cardiovascular, or neurological disease
  • Regular medication use
  • Current use of dietary supplements or ergogenic aids
  • Smoking or excessive alcohol consumption
  • Known hypersensitivity to any study supplement ingredient
  • Exclusion Criteria:

研究组 & 干预措施

P

Placebo Comparator

Participants will receive visually identical placebo capsules for 14 days.

干预措施: Placebo (Other)

TCP-300

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (300 mg/day) supplementation for 14 days.

干预措施: Caffeine (Dietary Supplement)

TC

Experimental

Participants will receive taurine (1500 mg/day) and caffeine (200 mg/day) supplementation for 14 days.

干预措施: Caffeine (Dietary Supplement)

TCP-300

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (300 mg/day) supplementation for 14 days.

干预措施: taurine (Dietary Supplement)

TCP-600

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (600 mg/day) supplementation for 14 days.

干预措施: taurine (Dietary Supplement)

TC

Experimental

Participants will receive taurine (1500 mg/day) and caffeine (200 mg/day) supplementation for 14 days.

干预措施: taurine (Dietary Supplement)

TCP-300

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (300 mg/day) supplementation for 14 days.

干预措施: Phosphatidylserine (Dietary Supplement)

TCP-600

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (600 mg/day) supplementation for 14 days.

干预措施: Caffeine (Dietary Supplement)

TCP-600

Experimental

Participants will receive taurine (1500 mg/day), caffeine (200 mg/day), and phosphatidylserine (600 mg/day) supplementation for 14 days.

干预措施: Phosphatidylserine (Dietary Supplement)

研究者

发起方
Vizja University in Warsaw
申办方类型
Other
责任方
Principal Investigator
主要研究者

Krzysztof Mizera

Principal Investigator

Vizja University in Warsaw

研究点 (5)

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